| Pimozide |
Influence on proteins |
Western Blot |
5.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
p-STAT5 |
|
| Pimozide |
Influence on proteins |
Western Blot |
5.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
STAT5 |
|
| Pimozide |
Influence on proteins |
Western Blot |
5.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
|
|
| Pimozide |
Influence on proteins |
Western Blot |
5.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
|
|
| Pimozide |
Influence on cell viability |
ATP-dependent luminescence assay |
1.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
|
|
| Pimozide |
Influence on cell viability |
ATP-dependent luminescence assay |
3.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
|
|
| Pimozide |
Influence on cell viability |
ATP-dependent luminescence assay |
5.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
|
|
| Pimozide |
Influence on cell viability |
ATP-dependent luminescence assay |
7.50 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
|
|
| Pimozide |
Influence on cell viability |
ATP-dependent luminescence assay |
10.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
|
|
| Pimozide |
Influence on cell viability |
ATP-dependent luminescence assay |
1.00 µM |
MV411 |
Homo sapiens |
|
|
|
| Pimozide |
Influence on cell viability |
ATP-dependent luminescence assay |
3.00 µM |
MV411 |
Homo sapiens |
|
|
|
| Pimozide |
Influence on cell viability |
ATP-dependent luminescence assay |
5.00 µM |
MV411 |
Homo sapiens |
|
|
|
| Pimozide |
Influence on cell viability |
ATP-dependent luminescence assay |
7.50 µM |
MV411 |
Homo sapiens |
|
|
|
| Pimozide |
Influence on cell viability |
ATP-dependent luminescence assay |
10.00 µM |
MV411 |
Homo sapiens |
|
|
|
| Pimozide |
Influence on proteins in presece of PKC412 |
Western Blot |
5.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
p-STAT5 |
|
| Pimozide |
Influence on proteins in presece of PKC412 |
Western Blot |
5.00 µM |
MV411 |
Homo sapiens |
|
p-STAT5 |
|
| Pimozide |
Influence on proteins in presece of PKC412 |
Western Blot |
5.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
STAT5 |
|
| Pimozide |
Influence on proteins in presece of PKC412 |
Western Blot |
5.00 µM |
MV411 |
Homo sapiens |
|
STAT5 |
|
| Pimozide |
Influence on cell viability in presence of PKC412 |
ATP-dependent luminescence assay |
5.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
|
|
| Pimozide |
Influence on cell apoptosis in presence of PKC412 |
Flow cytometry- Annexin |
5.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
|
|
| Pimozide |
Influence on protein activity in presence of sunitinib |
Western Blot |
5.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
p-STAT5 |
|
| Pimozide |
Influence on protein activity in presence of sunitinib |
Western Blot |
5.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
STAT5 |
|
| Pimozide |
Influence on cell viability in presence of sunitinib |
ATP-dependent luminescence assay |
5.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
|
|
| Pimozide |
Influence on cell apoptosis in presence of sunitinib |
Flow cytometry- Annexin |
5.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
|
|
| Pimozide |
Influence on protein activity |
Luciferase activity |
1.00 µM |
Reporter cell line |
Homo sapiens |
|
STAT1 luc |
|
| Pimozide |
Influence on protein activity |
Luciferase activity |
2.50 µM |
Reporter cell line |
Homo sapiens |
|
STAT1 luc |
|
| Pimozide |
Influence on protein activity |
Luciferase activity |
5.00 µM |
Reporter cell line |
Homo sapiens |
|
STAT1 luc |
|
| Pimozide |
Influence on protein activity |
Luciferase activity |
7.50 µM |
Reporter cell line |
Homo sapiens |
|
STAT1 luc |
|
| Pimozide |
Influence on protein activity |
Luciferase activity |
10.00 µM |
Reporter cell line |
Homo sapiens |
|
STAT1 luc |
|
| Pimozide |
Influence on protein activity |
Luciferase activity |
1.00 µM |
Reporter cell line |
Homo sapiens |
|
STAT3 luc |
|
| Pimozide |
Influence on protein activity |
Luciferase activity |
2.50 µM |
Reporter cell line |
Homo sapiens |
|
STAT3 luc |
|
| Pimozide |
Influence on protein activity |
Luciferase activity |
5.00 µM |
Reporter cell line |
Homo sapiens |
|
STAT3 luc |
|
| Pimozide |
Influence on protein activity |
Luciferase activity |
7.50 µM |
Reporter cell line |
Homo sapiens |
|
STAT3 luc |
|
| Pimozide |
Influence on protein activity |
Luciferase activity |
10.00 µM |
Reporter cell line |
Homo sapiens |
|
STAT3 luc |
|
| Pimozide |
Influence on protein activity |
Luciferase activity |
1.00 µM |
Reporter cell line |
Homo sapiens |
|
|
|
| Pimozide |
Influence on protein activity |
Luciferase activity |
2.50 µM |
Reporter cell line |
Homo sapiens |
|
|
|
| Pimozide |
Influence on protein activity |
Luciferase activity |
5.00 µM |
Reporter cell line |
Homo sapiens |
|
|
|
| Pimozide |
Influence on protein activity |
Luciferase activity |
7.50 µM |
Reporter cell line |
Homo sapiens |
|
|
|
| Pimozide |
Influence on protein activity |
Luciferase activity |
10.00 µM |
Reporter cell line |
Homo sapiens |
|
|
|
| Pimozide |
Influence on gene expression |
RT-qPCR |
5.00 µM |
KU812 |
Homo sapiens |
|
|
|
| Pimozide |
Influence on gene expression |
RT-qPCR |
5.00 µM |
KU812 |
Homo sapiens |
|
|
|
| Pimozide |
Influence on gene expression |
RT-qPCR |
5.00 µM |
KU812 |
Homo sapiens |
|
|
|
| Pimozide |
Influence on gene expression |
RT-qPCR |
5.00 µM |
KU812 |
Homo sapiens |
|
|
|
| Pimozide |
Influence on gene expression |
RT-qPCR |
5.00 µM |
KU812 |
Homo sapiens |
|
|
|
| Pimozide |
Influence on protein activity |
Western Blot |
1.00 µM |
KU812 |
Homo sapiens |
|
p-STAT5 |
|
| Pimozide |
Influence on protein activity |
Western Blot |
2.50 µM |
KU812 |
Homo sapiens |
|
p-STAT5 |
|
| Pimozide |
Influence on protein activity |
Western Blot |
5.00 µM |
KU812 |
Homo sapiens |
|
p-STAT5 |
|
| Pimozide |
Influence on protein activity |
Western Blot |
7.50 µM |
KU812 |
Homo sapiens |
|
p-STAT5 |
|
| Pimozide |
Influence on protein activity |
Western Blot |
10.00 µM |
KU812 |
Homo sapiens |
|
p-STAT5 |
|
| Pimozide |
Influence on protein activity |
Western Blot |
1.00 µM |
KU812 |
Homo sapiens |
|
STAT5 |
|
